Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.44 |
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22684760 | 0.92 | WDR91 (0.53) | PDE2AWDR91PTGS1TRPV1BACE1 | |
| SCHEMBL22684762 | 0.89 | PDE2A (0.42) | PDE2AWDR91PTGS1TRPV1HDAC3 | |
| SCHEMBL22684811 | 0.86 | WDR91 (0.41) | PDE2AWDR91CHRNA7TRPV1BACE1 | |
| SCHEMBL22657408 | 0.83 | MALT1 (0.45) | PDE2AWDR91PTGS1TRPV1HDAC3 | |
| SCHEMBL22685206 | 0.83 | PDE2A (0.48) | PDE2APTGS1HDAC3HDAC1HDAC2 | |
| SCHEMBL22686817 | 0.81 | PDE2A (0.46) | PDE2AWDR91PTGS1IDO1TRPV1 | |
| SCHEMBL22685074 | 0.81 | IDO1 (0.51) | PDE2AWDR91IDO1CHRNA7CYP2C9 | |
| SCHEMBL22685182 | 0.80 | PDE2A (0.41) | PDE2APTGS1TRPV1HDAC3HDAC1 | |
| SCHEMBL22685207 | 0.80 | PDE2A (0.43) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684761 | 0.80 | HDAC1 (0.44) | IDO1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |