Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685160 | 0.92 | WDR91 (0.41) | WDR91MCHR1AKT1S1PR3P2RX7 | |
| SCHEMBL22685095 | 0.87 | MCHR1 (0.39) | WDR91MCHR1AKT1S1PR3TP53 | |
| SCHEMBL22657410 | 0.83 | WDR91 (0.40) | WDR91AKT1TP53TSHRNFKB1 | |
| SCHEMBL22685471 | 0.81 | GPR119 (0.42) | WDR91MCHR1AKT1SMN1; SMN2HDAC1 | |
| SCHEMBL22685161 | 0.79 | PTPN1 (0.46) | MCHR1P2RX7PTPN1PTPN6PTPN11 | |
| SCHEMBL22685304 | 0.79 | BACE1 (0.39) | P2RX7PTPN1PTPN6PTPN11HDAC3 | |
| SCHEMBL22685172 | 0.78 | PTPN1 (0.44) | MCHR1AKT1P2RX7PTPN1PTPN6 | |
| SCHEMBL22685303 | 0.77 | HDAC3 (0.39) | WDR91AKT1S1PR3HDAC3HDAC1 | |
| SCHEMBL22685331 | 0.73 | AKT1 (0.38) | WDR91AKT1HDAC6BTKCTSL | |
| SCHEMBL22685332 | 0.73 | AKT1 (0.38) | WDR91AKT1HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047877-A | Novel amide compound and use thereof | 和记黄埔医药（上海）有限公司 | 2020-12-08 | — | — | CN | disclosed |
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |