Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 8/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686795 | 0.92 | BTK (0.38) | ABL1MAP4K4MINK1TNIKCTSL | |
| SCHEMBL22685197 | 0.89 | WDR91 (0.41) | WDR91ABL1MAP4K4MINK1TNIK | |
| SCHEMBL22684822 | 0.81 | WDR91 (0.40) | WDR91ABL1CTSLCTSBCTSS | |
| SCHEMBL22686796 | 0.80 | BTK (0.38) | CTSLCTSBCTSSPDE2AEGLN1 | |
| SCHEMBL22685308 | 0.79 | PDE10A (0.40) | CTSLCTSBCTSSEGLN1BTK | |
| SCHEMBL22685165 | 0.77 | WDR91 (0.42) | WDR91ABL1PDE2ABTK | |
| SCHEMBL22685198 | 0.77 | WDR91 (0.53) | WDR91ABL1MAP4K4 | |
| SCHEMBL22685311 | 0.76 | WDR91 (0.55) | WDR91ABL1MAP4K4 | |
| SCHEMBL22685086 | 0.74 | WDR91 (0.43) | WDR91PDE2A | |
| SCHEMBL22657417 | 0.71 | MKNK1 (0.45) | ABL1MAP4K4MINK1TNIKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |