Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 11/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686788 | 0.92 | HDAC3 (0.46) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685165 | 0.91 | WDR91 (0.42) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685197 | 0.88 | WDR91 (0.41) | WDR91MAP4K4ABL1KDM4E | |
| SCHEMBL22685311 | 0.86 | WDR91 (0.55) | WDR91MAP4K4ABL1MAPK1 | |
| SCHEMBL22685236 | 0.82 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6MAP4K4 | |
| SCHEMBL22685238 | 0.81 | HDAC3 (0.47) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686789 | 0.79 | WDR91 (0.43) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685351 | 0.78 | WDR91 (0.54) | WDR91MAP4K4KDM4E | |
| SCHEMBL22685237 | 0.77 | BTK (0.41) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686791 | 0.75 | WDR91 (0.44) | WDR91HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |