Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 11/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686789 | 0.92 | WDR91 (0.43) | WDR91MAP4K4HSD11B1DYRK1ADYRK1B | |
| SCHEMBL22685198 | 0.86 | WDR91 (0.53) | WDR91MAP4K4ABL1MAPK1 | |
| SCHEMBL22686788 | 0.78 | HDAC3 (0.46) | WDR91MAP4K4ABL1 | |
| SCHEMBL22685351 | 0.77 | WDR91 (0.54) | WDR91MAP4K4 | |
| SCHEMBL22685165 | 0.77 | WDR91 (0.42) | WDR91ABL1 | |
| SCHEMBL22685196 | 0.76 | WDR91 (0.42) | WDR91MAP4K4ABL1 | |
| SCHEMBL22685078 | 0.76 | WDR91 (0.53) | WDR91MAP4K4MAPK1 | |
| SCHEMBL22686783 | 0.76 | WDR91 (0.42) | WDR91MAP4K4 | |
| SCHEMBL22685237 | 0.75 | BTK (0.41) | WDR91MAP4K4ABL1HSD11B1 | |
| SCHEMBL22685249 | 0.74 | WDR91 (0.41) | WDR91MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |