Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 8/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685198 | 0.91 | WDR91 (0.53) | WDR91ABL1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685197 | 0.88 | WDR91 (0.41) | WDR91ABL1BTKPDE2AUSP7 | |
| SCHEMBL22685236 | 0.82 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6BTK | |
| SCHEMBL22686788 | 0.82 | HDAC3 (0.46) | WDR91ABL1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685072 | 0.77 | IDO1 (0.43) | WDR91ABL1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685196 | 0.77 | WDR91 (0.42) | WDR91ABL1BTKPDE2A | |
| SCHEMBL22685311 | 0.77 | WDR91 (0.55) | WDR91ABL1 | |
| SCHEMBL22684758 | 0.74 | WDR91 (0.43) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685238 | 0.71 | HDAC3 (0.47) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23908270 | 0.71 | WDR91 (0.56) | WDR91HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |