Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 6/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685347 | 0.91 | PDE2A (0.42) | PDE2AHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22685246 | 0.88 | WDR91 (0.45) | WDR91HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22685263 | 0.87 | HDAC3 (0.44) | WDR91HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22685345 | 0.86 | PDE2A (0.44) | WDR91PDE2AHDAC6HDAC3HDAC1 | |
| SCHEMBL22657408 | 0.84 | MALT1 (0.45) | WDR91PDE2AHDAC6HDAC3HDAC1 | |
| SCHEMBL22685183 | 0.82 | MALT1 (0.44) | WDR91HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL22686817 | 0.81 | PDE2A (0.46) | WDR91PDE2AHDAC6HDAC3HDAC1 | |
| SCHEMBL22684761 | 0.79 | HDAC1 (0.44) | HDAC6HDAC3HDAC1HDAC2MALT1 | |
| SCHEMBL22686808 | 0.79 | PDE2A (0.46) | WDR91PDE2AAKT1MALT1 | |
| SCHEMBL22685203 | 0.78 | PDE2A (0.47) | PDE2AHDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |