SCHEMBL2268533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2272931	0.88	KCNH2 (0.60)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2266762	0.88	CYP3A4 (0.60)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2272938	0.88	HTR6 (0.66)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2268905	0.87	HTR6 (0.59)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2269860	0.87	CYP3A4 (0.54)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2271085	0.84	CYP3A4 (0.47)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2273734	0.83	HTR6 (0.54)	HTR6CYP3A4DRD2HTR2AHTR7
	SCHEMBL2268934	0.82	CYP3A4 (0.57)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2274416	0.78	CYP3A4 (0.54)	HTR6CYP3A4KCNH2DRD2SLC6A2
	SCHEMBL2268401	0.77	CYP3A4 (0.60)	HTR6CYP3A4KCNH2DRD2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.