SCHEMBL2272938

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2268401	0.90	CYP3A4 (0.60)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2267658	0.89	KCNH2 (0.72)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2266759	0.89	CYP3A4 (0.72)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2268533	0.88	HTR6 (0.54)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2267880	0.88	CYP3A4 (0.60)	HTR6CYP3A4CYP2D6KCNH2DRD2
	Hydrochloric Acid SCHEMBL2268748	0.87	CYP3A4 (0.59)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2275148	0.86	CYP3A4 (0.56)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL1974004	0.85	HTR6 (0.68)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2268894	0.83	CYP3A4 (0.69)	HTR6CYP3A4CYP2D6KCNH2DRD2
	SCHEMBL2273734	0.81	HTR6 (0.54)	HTR6CYP3A4DRD2HTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.