Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929062 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL29133891 | 0.71 | POLB (0.54) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22044783 | 0.71 | POLB (0.54) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL28877109 | 0.69 | MAPT (0.52) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL11023725 | 0.69 | POLB (0.52) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22044364 | 0.69 | ESR1 (0.55) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL807863 | 0.66 | ALDH1A1 (0.70) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22554699 | 0.64 | ALDH1A1 (0.67) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22554727 | 0.64 | ALDH1A1 (0.67) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22051073 | 0.64 | ESR1 (0.49) | POLBALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513186-A1 | MULTIFUNCTIONAL ADDITIVES IN ENGINEERING THERMOPLASTICS | Cytec Technology Corp. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084583-A1 | MULTIFUNCTIONAL ADDITIVES IN ENGINEERING THERMOPLASTICS | CYTEC TECHNOLOGY CORP. (US) | 2011-07-14 | — | — | WO | disclosed |