Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betaine SCHEMBL6140458 | 0.88 | TSHR (0.45) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL907529 | 0.82 | TSHR (0.34) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL8807531 | 0.82 | BBOX1 (0.40) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL21712604 | 0.79 | TSHR (0.36) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL7974165 | 0.72 | TSHR (0.35) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL9330112 | 0.71 | TSHR (0.32) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL9344883 | 0.69 | — | — | |
| SCHEMBL640365 | 0.68 | — | — | |
| Betaine SCHEMBL23795787 | 0.67 | TSHR (0.33) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL3113299 | 0.67 | TSHR (0.45) | TSHRALDH1A1LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795346-B2 | Polishing liquid composition for silicon oxide film | KAO CORPORATION (JP) | 2023-10-24 | — | — | US | disclosed |
| US-20200369919-A1 | POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILM | KAO CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |