Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | CASP3 | P42574 | 4/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148310 | 0.87 | RAB9A (0.73) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12777019 | 0.86 | HSD17B10 (0.52) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12304267 | 0.85 | HSD17B10 (0.66) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL802768 | 0.84 | HSD17B10 (0.60) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL16972929 | 0.84 | HSD17B10 (0.60) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL28636530 | 0.84 | RAB9A (0.78) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9197515 | 0.84 | ESR1 (0.68) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL4159029 | 0.83 | NPC1 (0.67) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL27361354 | 0.82 | MAPT (0.66) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12304263 | 0.81 | KDM4E (0.62) | HSD17B10RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497712-B2 | Property modulation with chemical transformations | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-12-16 | — | — | US | disclosed |
| EP-3973534-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | The Regents Of The University Of Michigan (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |