Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584339 | 0.81 | HPGD (0.50) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL14070022 | 0.80 | LMNA (0.64) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL30657003 | 0.76 | LMNA (0.49) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL915300 | 0.76 | LMNA (0.49) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL21593782 | 0.74 | LMNA (0.43) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL30657001 | 0.73 | LMNA (0.69) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL29198713 | 0.73 | LMNA (0.69) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL4594814 | 0.71 | LMNA (0.59) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL22133239 | 0.71 | LMNA (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL2890802 | 0.71 | HPGD (0.59) | LMNAHPGDALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069732-B | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117069732-A | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2023-11-17 | — | — | CN | disclosed |
| US-10913770-B2 | Mertansine polypeptide conjugates | VISION GLOBAL HOLDINGS LIMITED (CN) | 2021-02-09 | — | — | US | disclosed |
| US-20200361988-A1 | MERTANSINE POLYPEPTIDE CONJUGATES | VISION GLOBAL HOLDINGS LIMITED (HK) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361988-A1 | MERTANSINE POLYPEPTIDE CONJUGATES | NGLY1, ANPEP, VIP | LMNA 2136/4885HPGD 3614/4885ALDH1A1 3769/4885 |
| US-10913770-B2 | Mertansine polypeptide conjugates | NGLY1, ANPEP, VIP | LMNA 2136/4885HPGD 3614/4885ALDH1A1 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.