SCHEMBL2268703

SCHEMBL2268703

BrCc1cc(Br)c(CBr)cc1Br

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
PTPN1 P18031 1/20 0.32
APEX1 P27695 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
SNCA P37840 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451101 0.94 ALOX15 (0.34) ALOX15ALOX12PTPN1
SCHEMBL14933499 0.90 ALOX15 (0.36) ALOX15ALOX12
SCHEMBL10524646 0.86 AHR (0.35) ALOX15ALOX12PTPN1APEX1CA1
SCHEMBL2528520 0.84 KDM1A (0.36) ALOX15ALOX12PTPN1
SCHEMBL16860939 0.84 AHR (0.31) ALOX15ALOX12
SCHEMBL16860902 0.84 DPP4 (0.33) ALOX15ALOX12PTPN1
SCHEMBL6827994 0.84 ALOX15 (0.34) ALOX15ALOX12
SCHEMBL10659064 0.84 ALOX15 (0.48) ALOX15ALOX12PTPN1CA1CA2
SCHEMBL11847346 0.84 ALDH1A1 (0.39) ALOX15ALOX12
SCHEMBL15788770 0.80 ALDH1A1 (0.36) ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912684-A Sulfonium salt cation adsorbent and preparation method and application thereof 中国科学院长春应用化学研究所 2025-05-02 CN claimed
CN-118440297-A Conductive polymer material, preparation method and application 北京大学深圳研究生院 2024-08-06 CN claimed
CN-116709872-A CsPbBr (I) with high stability 3 Quantum dot and preparation method of wide-color-gamut backlight device 北京科技大学 2023-09-05 CN claimed
CN-110563929-A pure organic room temperature phosphorescent material p-bromoaryl aldehyde substituted PPV derivative and preparation method thereof 上海大学 2019-12-13 CN claimed
US-12582641-B2 Sulfur-containing compound based on glutarimide skeleton and application thereof SHANGHAITECH UNIVERSITY (CN) 2026-03-24 US disclosed
US-20250297156-A1 CONJUGATED POLYMERS AND METHODS OF USE BioLegend, Inc. 2025-09-25 US disclosed
US-20250282621-A1 CARBON NANOTUBE COMPOSITE COMPRISING MECHANICAL L IGANDS NANOCORE APS (DK) 2025-09-11 US disclosed
US-12384964-B2 Conjugated polymers and methods of use BioLegend, Inc. (US) 2025-08-12 US disclosed
CN-119912684-A Sulfonium salt cation adsorbent and preparation method and application thereof 中国科学院长春应用化学研究所 2025-05-02 CN disclosed
WO-2025063197-A1 CRYSTAL, METHOD FOR PRODUCING CRYSTAL, AND METHOD FOR INDUCING SELF-ORGANIZATION OF SILANOL COMPOUND 国立研究開発法人産業技術総合研究所 2025-03-27 WO disclosed
CN-119431745-A Method for preparing macromer and macromer prepared thereby 百进生物科技公司 2025-02-14 CN disclosed
CN-111032823-B Conjugated polymers and methods of use thereof 百进生物科技公司 2024-12-20 CN disclosed
US-20030095958-A1 Inhibitors of bace VERTEX PHARMACEUTICALS INCORPORATED 2003-05-22 US disclosed
WO-2002088101-A2 INHIBITORS OF BACE VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-11-07 WO disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed
EP-0690086-B1 Conjugated polymers with ansa partial structures and their use as electroluminescent materials AVENTIS RES & TECH GMBH & CO (DE) 1999-11-17 EP disclosed
US-5712361-A Conjugated polymers containing ANSA substructures and their use as electroluminescence materials HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed
EP-0690086-A2 Conjugated polymers with ansa partial structures and their use as electroluminescent materials HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-03 EP disclosed
US-4171456-A α,α'-Bis(2-hydroxyethoxy)-2,3,5,6-tetrabromo-p-xylene ETHYL CORPORATION (US) 1979-10-16 US disclosed
US-4036809-A Halogen-containing diphosphonates ETHYL CORPORATION (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030095958-A1 Inhibitors of bace BACE2, BACE1, APP ALOX15 2946/4885ALOX12 3140/4885PTPN1 3956/4885
US-12582641-B2 Sulfur-containing compound based on glutarimide skeleton and application thereof SUCNR1, SRD5A1, GLS ALOX15 1460/4885ALOX12 1114/4885PTPN1 1366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.