Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.69 |
| ▸ | HTR2C | P28335 | 2/20 | 0.69 |
| ▸ | HTR7 | P34969 | 2/20 | 0.69 |
| ▸ | HRH1 | P35367 | 2/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 13/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266759 | 0.93 | CYP3A4 (0.72) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2267880 | 0.88 | CYP3A4 (0.60) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2268934 | 0.88 | CYP3A4 (0.57) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL2268748 | 0.87 | CYP3A4 (0.59) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL1975364 | 0.85 | HTR6 (0.68) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2268401 | 0.84 | CYP3A4 (0.60) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2272938 | 0.83 | HTR6 (0.66) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2267658 | 0.83 | KCNH2 (0.72) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2271622 | 0.83 | CYP3A4 (0.66) | CYP3A4CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2268980 | 0.81 | HTR6 (0.56) | CYP3A4CYP2D6DRD2SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998981-B2 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-16 | — | — | US | claimed |
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES, LTD. (IN) | 2010-07-01 | — | — | US | claimed |
| EP-1919896-B1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LTD (IN) | 2009-12-23 | — | — | EP | claimed |
| US-7998981-B2 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-16 | — | — | US | disclosed |
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES, LTD. (IN) | 2010-07-01 | — | — | US | disclosed |
| EP-1919896-B1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LTD (IN) | 2009-12-23 | — | — | EP | disclosed |
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | HTR6, HTR5A, HTR3B | CYP3A4 478/4885CYP2D6 50/4885DRD2 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.