Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704877 | 0.69 | SMN1; SMN2 (0.36) | ALDH1A1HPGDCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16907548 | 0.69 | CA1 (0.47) | ALDH1A1HTTRECQLSMN1; SMN2CA12 | |
| SCHEMBL23370091 | 0.67 | TDP1 (0.53) | ALDH1A1HTTPLCG1GAASMN1; SMN2 | |
| SCHEMBL2377998 | 0.67 | APLNR (0.58) | ALDH1A1HTTPLCG1L3MBTL1KMT2A | |
| SCHEMBL8933455 | 0.66 | POLB (0.59) | ALDH1A1ALOX12CYP2C19HTTPLCG1 | |
| SCHEMBL2339126 | 0.65 | CA1 (0.56) | HTTPLCG1CA12CA1CA2 | |
| SCHEMBL2717301 | 0.65 | KMT2A (0.57) | ALDH1A1HTTPLCG1KMT2ASMN1; SMN2 | |
| SCHEMBL20282082 | 0.64 | MAPT (0.55) | ALDH1A1HPGDALOX15HIF1AHSD17B10 | |
| SCHEMBL30496480 | 0.63 | PKM (0.56) | ALDH1A1HTTPLCG1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27633192 | 0.63 | KMT2A (0.55) | ALDH1A1HTTPLCG1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234424-A1 | BENZO[C][1,2,5]OXADIAZOLE FOR THE TREATMENT OF DISEASES CAUSED BY HELICOBACTER | UNIVERSIDAD DE ZARAGOZA (ES) | 2020-11-26 | — | — | WO | claimed |
| WO-2020234424-A1 | BENZO[C][1,2,5]OXADIAZOLE FOR THE TREATMENT OF DISEASES CAUSED BY HELICOBACTER | UNIVERSIDAD DE ZARAGOZA (ES) | 2020-11-26 | — | — | WO | disclosed |