Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911882 | 0.83 | TSHR (0.58) | POLBHTTALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL27472412 | 0.80 | L3MBTL1 (0.55) | POLBHTTALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL5051036 | 0.78 | KMT2A (0.47) | POLBHTTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5051033 | 0.78 | KMT2A (0.50) | POLBHTTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL11138536 | 0.76 | ALDH1A1 (0.46) | POLBHTTALDH1A1ALOX12KMT2A | |
| SCHEMBL29149689 | 0.75 | NFE2L2 (0.47) | POLBALDH1A1CYP1A2CYP3A4TP53 | |
| SCHEMBL8933453 | 0.75 | PKM (0.62) | ALDH1A1KMT2AMEN1KEAP1MMP1 | |
| SCHEMBL7077705 | 0.75 | ALDH1A1 (0.59) | POLBHTTALDH1A1LTA4HKEAP1 | |
| Anisole SCHEMBL11531120 | 0.74 | CA4 (0.54) | POLBALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL23554954 | 0.74 | KEAP1 (0.62) | HTTALDH1A1KMT2AMEN1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |