SCHEMBL2268940

SCHEMBL2268940

CCNCC(C)(C)[SiH2]c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.35
HTT P42858 2/20 0.32
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31
ADRB2 P07550 1/20 0.30
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2103816 0.91 KCNN4 (0.32) KCNN4
SCHEMBL2103507 0.81 CACNA2D1 (0.33) LMNACYP2D6KDM4E
SCHEMBL2272990 0.80 LMNA (0.36) KCNN4LMNACYP2D6KDM4ETSHR
SCHEMBL27943103 0.77 TP53 (0.35) KCNN4LMNACYP2D6TSHR
SCHEMBL2272708 0.71 TAAR1 (0.32) LMNACYP2D6
SCHEMBL19413917 0.69 TAAR1 (0.50) KCNN4
SCHEMBL2269750 0.69 MEN1 (0.37) LMNACYP2D6KDM4ETSHR
SCHEMBL28306477 0.69 GAA (0.37)
SCHEMBL15147452 0.69 RIPK1 (0.35) KCNN4LMNACYP2D6TSHR
SCHEMBL2273294 0.68 CYP2D6 (0.38) KCNN4LMNACYP2D6KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed