SCHEMBL2273294

SCHEMBL2273294

CN(C)CC(C)(C)[SiH2]c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.38
CYP2C19 P33261 3/20 0.38
CYP3A4 P08684 2/20 0.38
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.37
HTR2A P28223 2/20 0.34
HRH1 P35367 2/20 0.34
TAAR1 Q96RJ0 2/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KCNH2 Q12809 1/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
KCNN4 O15554 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269750 0.80 MEN1 (0.37) CYP2D6CYP2C19ALDH1A1TSHRSLC6A2
SCHEMBL27943103 0.76 TP53 (0.35) CYP2D6CYP2C19ALDH1A1TSHRTAAR1
SCHEMBL2272708 0.74 TAAR1 (0.32) CYP2D6TAAR1SLC6A2LMNA
SCHEMBL2272990 0.71 LMNA (0.36) CYP2D6CYP3A4ALDH1A1TSHRHTR2A
SCHEMBL1254751 0.69 MAPK1 (0.36) CYP2D6CYP2C19CYP3A4ALDH1A1TSHR
SCHEMBL2268940 0.68 KCNN4 (0.35) CYP2D6TSHRLMNAKDM4EKCNN4
SCHEMBL28306477 0.68 GAA (0.37) SMN1; SMN2
SCHEMBL9805626 0.68 KIF11 (0.47) CYP2D6CYP2C19CYP3A4CYP1A2HTR2A
Ethane SCHEMBL8430515 0.67 MAPK1 (0.35) CYP2D6CYP3A4ALDH1A1TSHRTAAR1
SCHEMBL15147452 0.67 RIPK1 (0.35) CYP2D6CYP2C19ALDH1A1TSHRTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed