Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18305914 | 0.79 | SLC22A16 (0.50) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| SCHEMBL52510 | 0.77 | MAPT (0.46) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL9486928 | 0.75 | MAPT (0.50) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| Iodide SCHEMBL6748621 | 0.75 | MAPT (0.44) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| SCHEMBL4059430 | 0.72 | — | — | |
| SCHEMBL16245141 | 0.72 | — | — | |
| SCHEMBL13158755 | 0.71 | MAPT (0.39) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| SCHEMBL27770459 | 0.70 | KISS1R (0.41) | — | |
| Acetic Acid SCHEMBL28210362 | 0.70 | MAPT (0.50) | CHRM2CHRM4CHRM1TSHRTBXA2R | |
| SCHEMBL9393610 | 0.69 | MAPT (0.42) | CHRM2CHRM4CHRM1TSHRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068819-A1 | NOVEL STRAIN HAVING ANTAGONISM AGAINST PROTEUS MIRABILIS AND EXCELLENT EFFECT ON NEURODEGENERATIVE DISEASE, AND USE THEREOF | 주식회사 메타센테라퓨틱스 | 2023-04-27 | — | — | WO | disclosed |
| US-10322209-B2 | Polyurethanes for osteoimplants | WARSAW ORTHOPEDIC, INC. (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180250442-A1 | POLYURETHANES FOR OSTEOIMPLANTS | WARSAW ORTHOPEDIC INC (US) | 2018-09-06 | — | — | US | disclosed |
| EP-1434608-B1 | IMPROVED BONE GRAFT | WARSAW ORTHOPEDIC INC (US) | 2018-08-22 | — | — | EP | disclosed |
| US-9993579-B2 | Polyurethanes for osteoimplants | WARSAW ORTHOPEDIC, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170304496-A1 | POLYURETHANES FOR OSTEOIMPLANTS | WARSAW ORTHOPEDIC INC (US) | 2017-10-26 | — | — | US | disclosed |
| US-9789223-B2 | Polyurethanes for osteoimplants | WARSAW ORTHOPEDIC, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170240698-A1 | Biodegradable Stealth Polymeric Particles Fabricated Using The Macromonomer Approach By Free Radical Dispersion Polymerization | HOWARD UNIVERSITY (US) | 2017-08-24 | — | — | US | disclosed |
| US-9675556-B2 | Biodegradable stealth polymeric particles fabricated using the macromonomer approach by free radical dispersion polymerization | HOWARD UNIVERSITY (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2295088-B1 | Improved bone graft | WARSAW ORTHOPEDIC INC (US) | 2016-12-07 | — | — | EP | disclosed |
| WO-1996002276-A9 | NOVEL POLYMER GEL NETWORKS AND METHODS OF USE | — | 1996-02-29 | — | — | WO | disclosed |
| WO-1996002239-A2 | ENHANCED LOADING OF SOLUTES INTO POLYMER GELS AND METHODS OF USE | UNIVERSITY OF CINCINNATI (US) | 1996-02-01 | — | — | WO | disclosed |
| WO-1996002276-A2 | NOVEL POLYMER GEL NETWORKS AND METHODS OF USE | GEL SCIENCES, INC. (US) | 1996-02-01 | — | — | WO | disclosed |
| WO-1994029306-A1 | COCAINE DERIVATIVES AND THEIR USE AS ANTICHOLINERGIC AGENTS | NEW YORK UNIVERSITY (US) | 1994-12-22 | — | — | WO | disclosed |
| EP-0584220-A1 | ENGINEERING THE LOCAL INFLAMMATORY RESPONSE AS A MEANS OF CONTROLLED RELEASE DRUG DELIVERY | ENDOCON, INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1993023012-A1 | LIQUID-CONTAINING DRUG DELIVERY SYSTEM | ENDOCON, INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1992020325-A1 | ENGINEERING THE LOCAL INFLAMMATORY RESPONSE AS A MEANS OF CONTROLLED RELEASE DRUG DELIVERY | ENDOCON, INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0178743-B1 | NOVEL TRITIUM LABELLED N-MUSTARD TYPE COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION | UNIVERSITY OF PITTSBURGH (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4795627-A | AZIRIDINIUM ANALOG USED TO EVALUATE THE MECHANISM OF NEUROTRANSMITTER REGULATION | UNIVERSITY OF PITTSBURGH (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0178743-A2 | Novel tritium labelled N-mustard type compounds and a process for their production | UNIVERSITY OF PITTSBURGH (US) | 1986-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240698-A1 | Biodegradable Stealth Polymeric Particles Fabricated Using The Macromonomer Approach By Free Radical Dispersion Polymerization | LDHA, LDHB, ALDH2 | CHRM2 2894/4885CHRM4 4483/4885CHRM1 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.