Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393966 | 0.91 | SMN1; SMN2 (0.47) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL12393969 | 0.91 | CASP3 (0.50) | CASP3KDM4EALDH1A1GAARORC | |
| SCHEMBL2267954 | 0.85 | TERT (0.47) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL2272366 | 0.84 | CYP1A2 (0.51) | CASP3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2267203 | 0.83 | TERT (0.45) | CASP3ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL2268733 | 0.83 | NPC1 (0.49) | ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL2274136 | 0.83 | L3MBTL1 (0.51) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2274239 | 0.82 | TERT (0.43) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL2269564 | 0.82 | POLB (0.45) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL712444 | 0.81 | TERT (0.50) | KDM4EALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530465-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-09-10 | — | — | US | claimed |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | HUANG HSU-SHAN (TW) | 2013-03-07 | — | — | US | claimed |
| US-8304415-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-11-06 | — | — | US | claimed |
| US-8530465-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-09-10 | — | — | US | disclosed |
| US-8530465-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-09-10 | — | — | US | disclosed |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | HUANG HSU-SHAN (TW) | 2013-03-07 | — | — | US | disclosed |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | HUANG HSU-SHAN (TW) | 2013-03-07 | — | — | US | disclosed |
| US-8304415-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-11-06 | — | — | US | disclosed |
| US-8304415-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA1, ANXA5, ANXA2 | CASP3 76/4885KDM4E 1987/4885ALDH1A1 1020/4885 |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA5, ANXA1, HCCS | CASP3 127/4885KDM4E 1255/4885ALDH1A1 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.