Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066334 | 0.82 | RIPK1 (0.50) | RIPK1ALDH1A1KDM4EMEN1GLA | |
| SCHEMBL27547538 | 0.75 | CA1 (0.45) | RIPK1ALDH1A1 | |
| SCHEMBL3679184 | 0.75 | SMN1; SMN2 (0.52) | RIPK1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL9843626 | 0.72 | PRKCZ (0.54) | RIPK1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL25370685 | 0.70 | MAPT (0.62) | RIPK1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL6225415 | 0.70 | CA1 (0.61) | ALDH1A1KDM4EGLAMAPTATM | |
| SCHEMBL27556930 | 0.70 | RIPK1 (0.44) | RIPK1ALDH1A1 | |
| SCHEMBL5693255 | 0.70 | PTGS2 (0.55) | RIPK1ALDH1A1KDM4EMEN1GLA | |
| SCHEMBL22689665 | 0.68 | ADORA2A (0.39) | RIPK1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL9380053 | 0.66 | RIPK1 (0.53) | RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020235902-A1 | HETEROCYCLE-FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF | 주식회사 보로노이 (KR) | 2020-11-26 | — | — | WO | claimed |