Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL233986 | 0.91 | GPR84 (0.50) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Phosphoric Acid SCHEMBL9353446 | 0.89 | GPR84 (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL29567690 | 0.84 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL155191 | 0.84 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20574564 | 0.83 | GPR84 (0.43) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL28628671 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10550137 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Methane SCHEMBL5065725 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28624457 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL27702719 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201027-A1 | BIOSENSOR FOR DETECTING A TRACE AMOUNT OF SAMPLE AND PRODUCTION METHOD THEREFOR | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2011-08-18 | — | — | US | disclosed |
| EP-0376480-B1 | Chlamydia assay | BECTON DICKINSON CO (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5030561-A | Colorimetric analysis; medical diagnosis | BECTON, DICKINSON AND COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0376480-A2 | Chlamydia assay | Becton, Dickinson and Company (US) | 1990-07-04 | — | — | EP | disclosed |