Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18973016 | 0.92 | NMT1 (0.48) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL18513361 | 0.91 | NMT2 (0.40) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL22857340 | 0.90 | NMT2 (0.40) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL24119975 | 0.89 | NMT2 (0.46) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL20099362 | 0.86 | NMT2 (0.53) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL22372632 | 0.86 | MEN1 (0.41) | NMT2NMT1NOD1NAMPTCNR1 | |
| SCHEMBL18879491 | 0.84 | GLP1R (0.49) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL20099252 | 0.84 | NMT2 (0.49) | NMT2NMT1NOD1GLP1RTLR2 | |
| SCHEMBL21415377 | 0.83 | TLR2 (0.43) | NOD1GLP1RTLR2EPHX2 | |
| SCHEMBL22692674 | 0.82 | NMT1 (0.52) | NMT2NMT1NOD1GLP1RTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844379-B2 | Conjugated antisense compounds and their use | IONIS PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844379-B2 | Conjugated antisense compounds and their use | CSGALNACT1, GALNT1, GALNT6 | NMT2 27/4885NMT1 30/4885NOD1 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.