Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155730 | 0.89 | CASP2 (0.54) | CASP2NOD1FAAHDNM1NAAA | |
| SCHEMBL22930200 | 0.89 | CASP2 (0.54) | CASP2NOD1FAAHDNM1NAAA | |
| SCHEMBL18513360 | 0.87 | MEN1 (0.40) | MEN1KMT2ACNR1NAMPTCASP2 | |
| SCHEMBL21003636 | 0.87 | CASP2 (0.53) | CASP2NOD1FAAHDNM1NAAA | |
| SCHEMBL24230584 | 0.86 | SLC6A5 (0.52) | CASP2NOD1FAAHDNM1NMT2 | |
| SCHEMBL22692648 | 0.86 | NMT2 (0.40) | CNR1NAMPTNOD1NMT2NMT1 | |
| SCHEMBL22022417 | 0.85 | NAMPT (0.38) | MEN1KMT2ACNR1NAMPTCASP2 | |
| SCHEMBL26773565 | 0.84 | NAMPT (0.41) | MEN1KMT2ACNR1NAMPTCASP2 | |
| SCHEMBL20099362 | 0.84 | NMT2 (0.53) | NOD1NMT2NMT1EPHX2 | |
| SCHEMBL20099252 | 0.82 | NMT2 (0.49) | NOD1NMT2NMT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270609-A1 | Single-Stranded RNAI Oligonucleotides Targeting APOC-III | IONIS PHARMACEUTICALS, INC. (US) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270609-A1 | Single-Stranded RNAI Oligonucleotides Targeting APOC-III | APOB, APOL1, RBM3 | MEN1 4557/4885KMT2A 1423/4885CNR1 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.