Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353826 | 0.98 | CYP3A4 (0.50) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28750395 | 0.82 | FAAH (0.41) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9802365 | 0.81 | MAPK9 (0.37) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27577364 | 0.80 | CYP3A4 (0.42) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5648367 | 0.80 | CYP2A6 (0.62) | CYP3A4CYP1A2ALDH1A1CYP2E1CYP2A6 | |
| SCHEMBL23196722 | 0.78 | CYP3A4 (0.44) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6609392 | 0.78 | MAPKAPK2 (0.43) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6608437 | 0.78 | NOTUM (0.41) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10594306 | 0.78 | ENPP2 (0.41) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6177595 | 0.78 | MKNK1 (0.43) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989126-B2 | Metal mercaptoimidazoles containing photoconductors | XEROX CORPORATION (US) | 2011-08-02 | — | — | US | claimed |
| US-20090274965-A1 | METAL MERCAPTOIMIDAZOLES CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-11-05 | — | — | US | claimed |
| US-7989126-B2 | Metal mercaptoimidazoles containing photoconductors | XEROX CORPORATION (US) | 2011-08-02 | — | — | US | disclosed |
| US-20090274965-A1 | METAL MERCAPTOIMIDAZOLES CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-11-05 | — | — | US | disclosed |