Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.46 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 8/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30415900 | 1.00 | FYN (0.47) | FYNNUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL17626654 | 0.86 | NUDT14 (0.48) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22692856 | 0.86 | ERBB2 (0.50) | FYNNUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL17911471 | 0.85 | TNK2 (0.47) | FYNNUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL200349 | 0.85 | NUDT14 (0.62) | FYNNUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL22243273 | 0.84 | PIK3CD (0.41) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| Hydrochloric Acid SCHEMBL29439185 | 0.84 | NUDT14 (0.61) | FYNNUDT14NUDT5PIK3CDPIK3CA | |
| SCHEMBL14617841 | 0.80 | BTK (0.52) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL18235468 | 0.79 | KDR (0.49) | NUDT14NUDT5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12713498 | 0.79 | PIK3CD (0.50) | FYNNUDT14NUDT5PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | BTK, FYN, YES1 | FYN 2/4885NUDT14 4860/4885NUDT5 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.