Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139169 | 0.81 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1PLK4PAK4ADORA3 | |
| SCHEMBL18701485 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1PDPK1HTTCHEK1 | |
| SCHEMBL13660393 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1ADORA3PDPK1HTT | |
| SCHEMBL26780067 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1ADORA3PDPK1HTT | |
| SCHEMBL7888421 | 0.76 | CHEK1 (0.40) | SGK1SMN1; SMN2ALDH1A1PLK4PAK4 | |
| SCHEMBL22402413 | 0.74 | NUDT1 (0.36) | SGK1SMN1; SMN2ALDH1A1ADORA3HTT | |
| SCHEMBL14570604 | 0.73 | ADORA2A (0.47) | SGK1SMN1; SMN2ALDH1A1PLK4PAK4 | |
| SCHEMBL61883 | 0.73 | PLK4 (0.53) | SGK1SMN1; SMN2ALDH1A1PLK4PAK4 | |
| SCHEMBL24224514 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1ADORA3HTT | |
| SCHEMBL23186713 | 0.71 | PDPK1 (0.32) | ALDH1A1PDPK1CHEK1AURKARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002118-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-01-06 | — | — | WO | disclosed |
| US-10844049-B2 | GLP-1R agonists and uses thereof | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844049-B2 | GLP-1R agonists and uses thereof | GLP1R, GPR119, GIPR | SGK1 2110/4885SMN1; SMN2 3477/4885ALDH1A1 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.