Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601885 | 0.85 | LMNA (0.34) | ALOX15TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11144533 | 0.82 | KDM1A (0.35) | ALOX15TSHR | |
| SCHEMBL11175804 | 0.76 | ADH1B (0.39) | ALOX15TSHRALDH1A1CYP2C19 | |
| SCHEMBL433370 | 0.74 | KMT2A (0.35) | ALOX15TSHRALDH1A1CYP3A4GGPS1 | |
| SCHEMBL2172460 | 0.73 | — | — | |
| SCHEMBL10045070 | 0.73 | KDM1A (0.42) | TSHRALDH1A1CYP1A2CYP2C19GGPS1 | |
| SCHEMBL12167806 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL22575455 | 0.71 | PAOX (0.35) | GGPS1FDFT1ABCG2 | |
| SCHEMBL10892665 | 0.71 | — | — | |
| Bromide SCHEMBL30398337 | 0.71 | PAOX (0.35) | GGPS1FDFT1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844163-B2 | Functional spirocyclic polymers and methods of preparation thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-24 | — | — | US | disclosed |