Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22693538 | 0.86 | AOC3 (0.53) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL16375197 | 0.82 | AOC3 (0.55) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL2204112 | 0.79 | MEN1 (0.62) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL22693539 | 0.75 | AOC3 (0.53) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL8230310 | 0.75 | AOC3 (0.53) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL14612259 | 0.73 | RAB9A (0.35) | MEN1KMT2A | |
| SCHEMBL16456038 | 0.73 | GRM5 (0.54) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL16456387 | 0.73 | GRM5 (0.54) | AOC3MEN1KMT2AGRM5 | |
| SCHEMBL21845102 | 0.71 | AOC3 (0.70) | AOC3 | |
| SCHEMBL20214501 | 0.71 | MEN1 (0.51) | AOC3MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | S1PR2, S1PR1, S1PR3 | AOC3 4293/4885MEN1 599/4885KMT2A 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.