SCHEMBL22694611

SCHEMBL22694611

CC(C)(C)c1cc(I)c(/C=N/Nc2nc3ccccc3s2)cc1I

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 18/20 0.53
▸ NPC1 O15118 13/20 0.53
▸ RAB9A P51151 12/20 0.53
▸ SMN1; SMN2 Q16637 11/20 0.53
▸ LMNA P02545 6/20 0.53
▸ KMT2A Q03164 13/20 0.50
▸ GAA P10253 13/20 0.50
▸ MEN1 O00255 12/20 0.50
▸ KDM4E B2RXH2 7/20 0.50
▸ TDP1 Q9NUW8 5/20 0.50
▸ NFKB1 P19838 4/20 0.50
▸ NFKB2 Q00653 4/20 0.50
▸ RELA Q04206 4/20 0.50
▸ MAPK1 P28482 4/20 0.50
▸ NPSR1 Q6W5P4 4/20 0.50
▸ POLB P06746 3/20 0.50
▸ TP53 P04637 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ GLA P06280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17693830 0.81 MAPT (0.51) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL21868809 0.80 MAPT (0.55) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL17693800 0.78 MAPT (0.48) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL18873374 0.73 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1132582 0.72 MAPT (0.58) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1132583 0.72 MAPT (0.58) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1231354 0.71 MAPT (0.70) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1231353 0.71 MAPT (0.70) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL22694605 0.71 NPC1 (0.36) MAPTNPC1RAB9ASMN1; SMN2GAA
SCHEMBL17123531 0.71 MAPT (0.67) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518938-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 — — US disclosed
US-11370970-B2 Optically anisotropic film, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-06-28 — — US disclosed
US-20200399538-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-12-24 — — US disclosed
US-20200369961-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-26 — — US disclosed
US-20200369960-A1 OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-11-26 — — US disclosed
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