SCHEMBL1231353

SCHEMBL1231353

C(=N/Nc1nc2ccccc2s1)\c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 16/20 0.70
▸ RAB9A P51151 13/20 0.70
▸ NPC1 O15118 13/20 0.70
▸ KMT2A Q03164 12/20 0.70
▸ MEN1 O00255 11/20 0.70
▸ GAA P10253 10/20 0.70
▸ SMN1; SMN2 Q16637 10/20 0.70
▸ KDM4E B2RXH2 5/20 0.70
▸ NFKB1 P19838 4/20 0.66
▸ NFKB2 Q00653 4/20 0.66
▸ RELA Q04206 4/20 0.66
▸ TDP1 Q9NUW8 3/20 0.66
▸ NPSR1 Q6W5P4 2/20 0.66
▸ POLB P06746 1/20 0.66
▸ PAX8 Q06710 1/20 0.66
▸ LMNA P02545 5/20 0.65
▸ MAPK1 P28482 3/20 0.65
▸ TP53 P04637 2/20 0.63
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ HPGD P15428 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231354 1.00 MAPT (0.70) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL10038665 0.90 MAPT (0.65) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL1165591 0.88 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL1165592 0.88 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL28684828 0.88 MAPT (0.61) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL21010612 0.85 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL13779288 0.82 MAPT (0.75) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL22103769 0.81 MAPT (0.64) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL27701871 0.81 MAPT (0.62) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL17123531 0.81 MAPT (0.67) MAPTRAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8617897-B2 Method of detecting oxides of nitrogen 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-31 — — US claimed
EP-2462441-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M Innovative Properties Company (US) 2012-06-13 — — EP claimed
US-20120129266-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY 2012-05-24 — — US claimed
WO-2011017317-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-10 — — WO claimed
EP-3789472-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2025-04-16 — — EP disclosed
US-11914248-B2 Photo-alignment copolymer, photo-alignment film, and optical laminate FUJIFILM CORPORATION (JP) 2024-02-27 — — US disclosed
US-20230296820-A1 POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-21 — — US disclosed
US-11746295-B2 Polymerizable liquid crystal composition, optically anisotropic film, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-09-05 — — US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 — — US disclosed
US-11726367-B2 Phase difference film, method for manufacturing phase difference film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-15 — — US disclosed
US-20230228928-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY FUJIFILM CORPORATION (JP) 2023-07-20 — — US disclosed
US-20230183574-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-15 — — US disclosed
US-20160015835-A1 LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-01-21 — — US disclosed
US-9173966-B2 Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-11-03 — — US disclosed
US-20150072966-A1 METHOD OF PROMOTING WOUND HEALING 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-12 — — US disclosed
US-8617897-B2 Method of detecting oxides of nitrogen 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-31 — — US disclosed
US-20130287699-A1 Luciferin Derivatives from Bicyclic Reactants and Aminothiol Derivatives and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2013-10-31 — — US disclosed
EP-2462441-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M Innovative Properties Company (US) 2012-06-13 — — EP disclosed
US-20120129266-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY 2012-05-24 — — US disclosed
WO-2011017317-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130287699-A1 Luciferin Derivatives from Bicyclic Reactants and Aminothiol Derivatives and Methods of Use Thereof GFPT1, QPCT, GLB1 MAPT 3324/4885RAB9A 4461/4885NPC1 3707/4885
US-20150072966-A1 METHOD OF PROMOTING WOUND HEALING NOS3, NOS1, NOS2 MAPT 4876/4885RAB9A 2130/4885NPC1 4456/4885
US-20160015835-A1 LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF GFPT1, QPCT, GLB1 MAPT 3324/4885RAB9A 4461/4885NPC1 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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