Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26495374 | 0.77 | CCR5 (0.47) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22795906 | 0.72 | CCR5 (0.42) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20664448 | 0.72 | CCR5 (0.42) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25164998 | 0.72 | CCR5 (0.42) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24162636 | 0.72 | CCR5 (0.42) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25165362 | 0.72 | CCR5 (0.42) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL22773673 | 0.70 | CCR5 (0.40) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL29596889 | 0.70 | CCR5 (0.40) | CCR5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22171800 | 0.69 | — | — | |
| SCHEMBL24404137 | 0.69 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292378-B | Indole derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020233669-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |