SCHEMBL25165362

SCHEMBL25165362

CC1(O)C[C@H]2CNC[C@H]2C1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 1/20 0.42
CHRNB2 P17787 6/20 0.34
CHRNA4 P43681 6/20 0.34
CHRNB4 P30926 5/20 0.34
CHRNA3 P32297 5/20 0.34
CHRNA7 P36544 4/20 0.32
MAN1B1 Q9UKM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25164998 1.00 CCR5 (0.42) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL22795906 1.00 CCR5 (0.42) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL22773673 0.97 CCR5 (0.40) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL29596889 0.97 CCR5 (0.40) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL26495374 0.77 CCR5 (0.47) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL14280949 0.74 CHRNB2 (0.31) CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7
SCHEMBL13005174 0.74 CHRNB2 (0.39) CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7
SCHEMBL22695220 0.72 CCR5 (0.42) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL20664448 0.72 CCR5 (0.42) CCR5CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL24162636 0.72 CCR5 (0.42) CCR5CHRNB2CHRNA4CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023061294-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 再鼎医药(上海)有限公司 2023-04-20 WO disclosed