SCHEMBL2269645

SCHEMBL2269645

CCCCCCOC(=O)CN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.70
NAAA Q02083 1/20 0.69
RAD52 P43351 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
DGKA P23743 1/20 0.57
FAAH O00519 2/20 0.56
EPHX1 P07099 1/20 0.53
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
TSHR P16473 3/20 0.52
HCAR2 Q8TDS4 1/20 0.48
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
DNM1 Q05193 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27918118 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL6380882 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL7780438 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL580166 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL972977 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL410582 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL10626588 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL5153816 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL2763091 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL27505167 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117987108-A Polymer crosslinking system with siloxane structure for deep profile control 中国海洋石油集团有限公司 2024-05-07 CN claimed
CN-114016094-B Leveling agent and preparation method thereof 深圳市励高表面处理材料有限公司 2022-11-18 CN claimed
CN-114016094-A Leveling agent and preparation method thereof 深圳市励高表面处理材料有限公司 2022-02-08 CN claimed
US-10143969-B2 Compounds for the capture of carbon dioxide from gaseous mixtures and subsequent release, related process and plant UNIVERSITA DEGLI STUDI DI MILANO-BICOCCA (IT) 2018-12-04 US claimed
US-20160346734-A1 NOVEL COMPOUNDS FOR THE CAPTURE OF CARBON DIOXIDE FROM GASEOUS MIXTURES AND SUBSEQUENT RELEASE, RELATED PROCESS AND PLANT UNIVERSITA DEGLI STUDI DI MILANO-BICOCCA (IT) 2016-12-01 US claimed
EP-3094399-A2 NOVEL COMPOUNDS FOR THE CAPTURE OF CARBON DIOXIDE FROM GASEOUS MIXTURES AND SUBSEQUENT RELEASE, RELATED PROCESS AND PLANT Università Degli Studi Di Milano - Bicocca (IT) 2016-11-23 EP claimed
CN-102300870-B Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same OTSUKA CHEMICAL CO LTD 2014-12-03 CN claimed
EP-1463823-B1 METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) FIBROGEN INC (US) 2013-03-06 EP claimed
US-20100261909-A1 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles SANOFI-AVENTIS (FR) 2010-10-14 US claimed
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI-AVENTIS (FR) 2010-08-26 US claimed
EP-2173747-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
EP-2173721-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
WO-2009000413-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI-AVENTIS (FR) 2008-12-31 WO claimed
WO-2009000412-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI AVENTIS (FR) 2008-12-31 WO claimed
CN-1374969-A FAP-activated anti-tumor compounds BOEHRINGER SOHN INGELHEIM (DE) 2002-10-16 CN claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN disclosed
CN-1093743-A The microemulsion cleaning composition that contains ethylene glycol-alkyl oxide COLGATE PALMOLIVE CO (US) 1994-10-19 CN disclosed
CN-1089269-A Novel 5-amino-4-hydroxy caproic acid derivative as therapeutical agent CIBA GEIGY AG (CH) 1994-07-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261909-A1 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles AZI2, NISCH, UQCRB HTR2C 1788/4885NAAA 347/4885RAD52 713/4885
US-10143969-B2 Compounds for the capture of carbon dioxide from gaseous mixtures and subsequent release, related process and plant GK, AGXT, GHDC HTR2C 1561/4885NAAA 442/4885RAD52 4540/4885
US-20160346734-A1 NOVEL COMPOUNDS FOR THE CAPTURE OF CARBON DIOXIDE FROM GASEOUS MIXTURES AND SUBSEQUENT RELEASE, RELATED PROCESS AND PLANT GK, AGXT, GHDC HTR2C 1643/4885NAAA 399/4885RAD52 4633/4885
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles AZI2, NIT2, NISCH HTR2C 2194/4885NAAA 325/4885RAD52 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.