SCHEMBL580166

SCHEMBL580166

CCCCCCCCOC(=O)CN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.70
NAAA Q02083 1/20 0.69
RAD52 P43351 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
DGKA P23743 1/20 0.57
FAAH O00519 2/20 0.56
EPHX1 P07099 1/20 0.53
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
TSHR P16473 3/20 0.52
HCAR2 Q8TDS4 1/20 0.48
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
DNM1 Q05193 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27918118 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL6380882 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL7780438 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL2269645 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL972977 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL410582 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL10626588 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL5153816 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL2763091 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA
SCHEMBL27505167 1.00 HTR2C (0.70) HTR2CNAAARAD52NPSR1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025080555-A1 SUBSTITUTED AMIDINE IONIZABLE LIPID COMPOUNDS, METHODS OF PREPARATION THEREOF, LIPID NANOPARTICLES (LNPS) COMPRISING THE SAME, AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-17 WO claimed
CN-117987108-A Polymer crosslinking system with siloxane structure for deep profile control 中国海洋石油集团有限公司 2024-05-07 CN claimed
CN-116840387-A Potential typing metabolic marker for nephrotic syndrome and metabolic marker related to lesion process and application of potential typing metabolic marker 山西大学 2023-10-03 CN claimed
CN-114478870-B Catalyst system for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-06-06 CN claimed
CN-114507303-B External electron donor for olefin polymerization, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2023-05-05 CN claimed
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2018-11-01 US claimed
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2017-06-29 US claimed
CN-103889442-B Injectable solution of at least one basal insulin 阿道恰公司 2016-12-28 CN claimed
EP-2741765-B9 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-09-28 EP claimed
EP-2741765-B1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-03-30 EP claimed
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2015-09-10 US claimed
US-9089476-B2 Injectable solution at pH 7 comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2015-07-28 US claimed
CN-103889442-A Injectable solution of at least one basal insulin ADOCIA 2014-06-25 CN claimed
CN-101664553-B Stabilization of hypoxia inducible factor (HIF) alpha FIBROGEN INC 2013-08-21 CN claimed
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2013-03-14 US claimed
EP-1463823-B1 METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) FIBROGEN INC (US) 2013-03-06 EP claimed
EP-4554959-A2 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE Pep2Tango Therapeutics Inc. (US) 2025-05-21 EP disclosed
WO-2025080555-A1 SUBSTITUTED AMIDINE IONIZABLE LIPID COMPOUNDS, METHODS OF PREPARATION THEREOF, LIPID NANOPARTICLES (LNPS) COMPRISING THE SAME, AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-17 WO disclosed
EP-0119471-A2 An active hydrogen-containing composition which provides mold release properties to a molded article, and a process for preparing molded polymeric products from the active hydrogen-containing composition THE DOW CHEMICAL COMPANY (US) 1984-09-26 EP disclosed
WO-1984003288-A1 AN ACTIVE HYDROGEN-CONTAINING COMPOSITION WHICH PROVIDES MOLD RELEASE PROPERTIES TO A MOLDED ARTICLE, AN INTERNAL MOLD RELEASE COMPOSITION FOR PREPARING THE ACTIVE HYDROGEN-CONTAINING COMPOSITION, AND A PROCESS FOR PREPARING MOLDED POLYMERIC PRODUCTS FROM THE ACTIVE HYDROGEN-CONTAINING COMPOSITION DOW CHEMICAL CO (US) 1984-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR HTR2C 3723/4885NAAA 3588/4885RAD52 4290/4885
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR HTR2C 3723/4885NAAA 3588/4885RAD52 4290/4885
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR HTR2C 3723/4885NAAA 3588/4885RAD52 4290/4885
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 IAPP, IGFBP5, INSR HTR2C 3723/4885NAAA 3588/4885RAD52 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.