Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076545 | 0.82 | ALDH1A1 (0.49) | TP53MAPTTHRBL3MBTL1POLB | |
| SCHEMBL17466017 | 0.81 | MAPT (0.58) | TP53MAPTTHRBPOLBTDP1 | |
| SCHEMBL21914195 | 0.77 | TSHR (0.42) | THRBL3MBTL1POLBTDP1SMN1; SMN2 | |
| SCHEMBL9323699 | 0.74 | ALDH1A1 (0.42) | TP53MAPTTHRBL3MBTL1POLB | |
| SCHEMBL25916881 | 0.70 | POLB (0.46) | MAPTTHRBL3MBTL1POLBTDP1 | |
| SCHEMBL24050687 | 0.70 | THRB (0.36) | MAPTTHRBPOLBTDP1KDM4E | |
| SCHEMBL22697144 | 0.68 | TP53 (0.59) | TP53MAPTTHRBPOLBTDP1 | |
| SCHEMBL51038 | 0.67 | ALDH1A1 (0.55) | TP53MAPTL3MBTL1POLBTDP1 | |
| SCHEMBL25863970 | 0.66 | TSHR (0.40) | THRBL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL17465804 | 0.66 | MAPT (0.57) | TP53MAPTTHRBL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |