Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17466000 | 0.92 | TP53 (0.67) | TP53MAPTTHRBDNM1POLB | |
| SCHEMBL22697146 | 0.89 | TP53 (0.63) | TP53MAPTTHRBDNM1POLB | |
| SCHEMBL17465992 | 0.85 | TP53 (0.62) | TP53MAPTTHRBDNM1POLB | |
| SCHEMBL17465797 | 0.78 | POLB (0.73) | TP53MAPTTHRBDNM1POLB | |
| SCHEMBL7106941 | 0.75 | DNM1 (0.57) | TP53MAPTDNM1POLBALDH1A1 | |
| SCHEMBL7106944 | 0.75 | DNM1 (0.57) | TP53MAPTDNM1POLBALDH1A1 | |
| SCHEMBL17465995 | 0.75 | ALDH1A1 (0.60) | TP53MAPTDNM1POLBTDP1 | |
| SCHEMBL19829845 | 0.74 | DNM1 (0.63) | TP53MAPTDNM1TDP1ALDH1A1 | |
| SCHEMBL994759 | 0.74 | DNM1 (0.60) | TP53MAPTTHRBDNM1TDP1 | |
| SCHEMBL994758 | 0.74 | DNM1 (0.60) | TP53MAPTTHRBDNM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |