SCHEMBL22698378

SCHEMBL22698378

Clc1cncc2oc3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AHR P35869 2/20 0.35
HDAC4 P56524 1/20 0.34
BTK Q06187 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3R1 P27986 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22698388 0.92 KDM4E (0.38) ATMKDM4EL3MBTL1AHRHDAC4
SCHEMBL22698400 0.84 AHR (0.43) KDM4EL3MBTL1AHRPLA2G2APLA2G4A
SCHEMBL23814107 0.81 PLA2G2A (0.39) ATMKDM4EL3MBTL1AHRHDAC4
SCHEMBL16804580 0.81 KDM4E (0.50) ATMKDM4EL3MBTL1AHRHDAC4
SCHEMBL22698398 0.81 L3MBTL1 (0.34) ATMKDM4EL3MBTL1HDAC4BTK
SCHEMBL26169505 0.80 KDM4E (0.43) ATMKDM4EL3MBTL1AHRHDAC4
SCHEMBL9890573 0.80 KDM4E (0.42) ATMKDM4EL3MBTL1AHRHDAC4
SCHEMBL22698381 0.79 LPL (0.33) ATMKDM4EL3MBTL1HDAC4
SCHEMBL30459395 0.79 KDM4E (0.44) ATMKDM4EL3MBTL1AHRPLA2G2A
SCHEMBL25257176 0.79 KDM4E (0.44) ATMKDM4EL3MBTL1AHRPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed