Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409537 | 0.85 | CTSL (0.47) | TDP1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL17161708 | 0.85 | MEN1 (0.62) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3190680 | 0.80 | MEP1B (0.53) | MEP1BTDP1KDM4EMEN1KMT2A | |
| SCHEMBL19474705 | 0.80 | MEP1B (0.74) | MEP1BTDP1MEN1KMT2AMEP1A | |
| SCHEMBL14460020 | 0.80 | GAA (0.70) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL1290016 | 0.79 | MEP1B (0.49) | MEP1BTDP1KDM4EMEN1KMT2A | |
| SCHEMBL4710939 | 0.79 | GAA (0.56) | MEP1BTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9721530 | 0.79 | MEP1B (0.55) | MEP1BTDP1KDM4EMEN1KMT2A | |
| SCHEMBL27650715 | 0.77 | MEN1 (0.60) | MEP1BTDP1KDM4EMEN1KMT2A | |
| SCHEMBL21138111 | 0.76 | GAA (0.56) | TDP1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |