Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363144 | 0.87 | SYK (0.52) | SYKCTSLCTSSCTRB1ELANE | |
| SCHEMBL29181922 | 0.87 | SYK (0.52) | SYKCTSLCTSSCTRB1ELANE | |
| SCHEMBL5362813 | 0.86 | CTRB1 (0.50) | SYKCTSLCTSSCTRB1ATM | |
| SCHEMBL10050950 | 0.83 | OPRK1 (0.48) | SYKCTSLCTSSCTRB1ATM | |
| SCHEMBL10050609 | 0.83 | OPRK1 (0.48) | SYKCTSLCTSSCTRB1ATM | |
| SCHEMBL22754646 | 0.82 | ATM (0.54) | CTSLCTSSCTRB1ELANECTSB | |
| SCHEMBL937972 | 0.81 | ATM (0.57) | CTSLCTSSCTRB1ELANECTSB | |
| SCHEMBL937973 | 0.81 | ATM (0.57) | CTSLCTSSCTRB1ELANECTSB | |
| SCHEMBL13201865 | 0.81 | SYK (0.56) | SYKCTSLCTSSCTRB1ELANE | |
| SCHEMBL29014283 | 0.80 | SYK (0.57) | SYKCTSLCTSSCTRB1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |