Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050609 | 0.88 | OPRK1 (0.48) | CTRB1CTSLCTSSOPRK1MEN1 | |
| SCHEMBL10050950 | 0.88 | OPRK1 (0.48) | CTRB1CTSLCTSSOPRK1MEN1 | |
| SCHEMBL22698698 | 0.86 | SYK (0.51) | CTRB1CTSLCTSSOPRK1MEN1 | |
| SCHEMBL7405303 | 0.80 | CTRB1 (0.55) | CTRB1CTSLCTSSALDH1A1LMNA | |
| SCHEMBL758144 | 0.78 | CTRB1 (0.54) | CTRB1CTSLCTSSOPRK1MEN1 | |
| SCHEMBL22118319 | 0.78 | CTRB1 (0.54) | CTRB1LMNASMN1; SMN2HTTATM | |
| SCHEMBL7372388 | 0.78 | CTRB1 (0.54) | CTRB1LMNASMN1; SMN2HTTATM | |
| SCHEMBL8173806 | 0.78 | CTRB1 (0.54) | CTRB1LMNASMN1; SMN2HTTATM | |
| SCHEMBL937973 | 0.78 | ATM (0.57) | CTRB1CTSLCTSSATMCTSK | |
| SCHEMBL937972 | 0.78 | ATM (0.57) | CTRB1CTSLCTSSATMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189680-B2 | 5-halo-6-aryl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7189680-B2 | 5-halo-6-aryl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7189680-B2 | 5-halo-6-aryl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7186831-B2 | 5-halo-2-alkyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE LP (DE) | 2007-03-06 | — | — | US | disclosed |
| US-7186831-B2 | 5-halo-2-alkyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE LP (DE) | 2007-03-06 | — | — | US | disclosed |
| US-7186831-B2 | 5-halo-2-alkyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines | BAYER CROPSCIENCE LP (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | disclosed |
| US-20040176398-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
| US-20040157863-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20040142943-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | CTRB1 864/4885CTSL 4394/4885CTSS 4263/4885 |
| US-20040157863-A1 | Triazolopyrimidines | Q6ZSR9, UMPS, MRPL21 | CTRB1 2453/4885CTSL 4275/4885CTSS 3203/4885 |
| US-20040176398-A1 | Triazolopyrimidines | Q6ZSR9, UMPS, UPP1 | CTRB1 1024/4885CTSL 3615/4885CTSS 1685/4885 |
| US-20040142943-A1 | Triazolopyrimidines | Q6ZSR9, UMPS, ARG1 | CTRB1 1115/4885CTSL 3325/4885CTSS 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.