Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 9/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25773953 | 0.90 | BMP1 (0.37) | FURINCTSLNMT2NMT1SIRT6 | |
| SCHEMBL29385639 | 0.89 | C3AR1 (0.45) | FURINC3AR1 | |
| SCHEMBL22524830 | 0.88 | C3AR1 (0.41) | NMT2NMT1SIRT6SIRT1BMP1 | |
| SCHEMBL25773985 | 0.88 | FURIN (0.40) | FURINCTSLNMT2NMT1SIRT6 | |
| SCHEMBL23736705 | 0.87 | FURIN (0.36) | FURINNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20795891 | 0.87 | FURIN (0.36) | FURINNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20159819 | 0.87 | FURIN (0.36) | FURINNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL31454057 | 0.87 | FURIN (0.42) | FURINCTSLNMT2NMT1SIRT6 | |
| SCHEMBL17752431 | 0.86 | NMT2 (0.41) | FURINCTSLNMT2NMT1PRSS1 | |
| SCHEMBL16091800 | 0.86 | NMT2 (0.41) | FURINCTSLNMT2NMT1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |