Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.36 |
| ▸ | BMP1 | P13497 | 3/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20795891 | 1.00 | FURIN (0.36) | FURINBMP1C3AR1SIRT6SIRT1 | |
| SCHEMBL20159819 | 1.00 | FURIN (0.36) | FURINBMP1C3AR1SIRT6SIRT1 | |
| SCHEMBL23236822 | 0.90 | BMP1 (0.36) | FURINBMP1C3AR1SIRT6SIRT1 | |
| SCHEMBL21788077 | 0.90 | FURIN (0.38) | FURINC3AR1SIRT6SIRT1SIRT5 | |
| SCHEMBL27352679 | 0.90 | FURIN (0.38) | FURINC3AR1SIRT6SIRT1SIRT5 | |
| SCHEMBL23393940 | 0.90 | SIRT5 (0.39) | FURINC3AR1SIRT5LMNAPOLB | |
| SCHEMBL22045351 | 0.89 | FURIN (0.39) | FURINC3AR1SIRT6SIRT1SIRT5 | |
| SCHEMBL22351933 | 0.89 | FURIN (0.37) | FURINBMP1C3AR1SIRT6SIRT1 | |
| SCHEMBL21897483 | 0.89 | FURIN (0.39) | FURINBMP1C3AR1SIRT6SIRT1 | |
| SCHEMBL17758699 | 0.89 | FURIN (0.37) | FURINBMP1C3AR1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| EP-3862023-A1 | CONJUGATES OF CELL-BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou DAC Biotech Co, Ltd (CN) | 2021-08-11 | — | — | EP | disclosed |