Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 7/20 | 0.51 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.42 |
| ▸ | BCL2 | P10415 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700362 | 0.86 | MCL1 (0.62) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL2622249 | 0.78 | AKR1B1 (0.72) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700667 | 0.78 | MCL1 (0.69) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700701 | 0.75 | MCL1 (0.70) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700547 | 0.75 | MCL1 (0.60) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL2622263 | 0.68 | AKR1B1 (1.00) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700781 | 0.68 | ALB (0.67) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700525 | 0.67 | MCL1 (0.64) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL30143404 | 0.67 | MCL1 (0.66) | AKR1B1ALBMCL1BCL2KDM4E | |
| SCHEMBL22700384 | 0.67 | MCL1 (0.71) | AKR1B1ALBMCL1BCL2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | Nearmedic International Limited (CY) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | DNM2, DNM1, MAVS | AKR1B1 1151/4885ALB 674/4885MCL1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.