Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.50 |
| ▸ | BCL2 | P10415 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700377 | 0.82 | AKR1B1 (0.57) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700666 | 0.76 | AKR1B1 (0.53) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL17372966 | 0.75 | MCL1 (0.82) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700655 | 0.75 | AKR1B1 (0.60) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700495 | 0.74 | MCL1 (0.76) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700662 | 0.73 | MCL1 (0.62) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700375 | 0.72 | KDM4E (0.41) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL22700528 | 0.72 | MCL1 (0.60) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700773 | 0.72 | MCL1 (0.67) | AKR1B1MCL1BCL2KDM4EMEN1 | |
| SCHEMBL22700661 | 0.71 | AKR1B1 (0.50) | AKR1B1MCL1BCL2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | Nearmedic International Limited (CY) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | DNM2, DNM1, MAVS | AKR1B1 1151/4885MCL1 3671/4885BCL2 3675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.