Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 12/20 | 0.54 |
| ▸ | LDHA | P00338 | 2/20 | 0.54 |
| ▸ | LDHB | P07195 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.52 |
| ▸ | BCL2 | P10415 | 6/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.52 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700785 | 0.88 | ALB (0.68) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL22700394 | 0.86 | MCL1 (0.69) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL22700782 | 0.83 | MCL1 (0.53) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL22700781 | 0.74 | ALB (0.67) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL22700373 | 0.74 | MCL1 (0.60) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL1150308 | 0.73 | MCL1 (0.76) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL22700384 | 0.73 | MCL1 (0.71) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL30143382 | 0.73 | MCL1 (0.69) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL30143506 | 0.72 | MCL1 (0.77) | AKR1B1LDHALDHBMCL1BCL2 | |
| SCHEMBL14959261 | 0.72 | MCL1 (0.77) | AKR1B1LDHALDHBMCL1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | Nearmedic International Limited (CY) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369618-A1 | ASYMMETRIC DERIVATIVES OF POLYPHENOLS OF THE DINAPHTHALINE SERIES, PROCESS OF PREPARING AND USE THEREOF | DNM2, DNM1, MAVS | AKR1B1 1151/4885LDHA 2403/4885LDHB 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.