Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LDLR | P01130 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388399 | 0.82 | KMT2A (0.40) | L3MBTL1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL1710677 | 0.81 | KMT2A (0.38) | L3MBTL1MEN1KMT2ALDLRNPC1 | |
| SCHEMBL3387847 | 0.73 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ALDLRNPC1 | |
| SCHEMBL14139168 | 0.72 | TPMT (0.48) | KMT2ASMYD3KDM4ELMNAHDAC3 | |
| SCHEMBL1722558 | 0.71 | SMN1; SMN2 (0.43) | MEN1KMT2ALDLRNPC1RAB9A | |
| SCHEMBL1726498 | 0.68 | KMT2A (0.35) | L3MBTL1MEN1KMT2ALDLRNPC1 | |
| SCHEMBL22700895 | 0.67 | MEN1 (0.34) | L3MBTL1MEN1KMT2ALDLRNPC1 | |
| SCHEMBL1725661 | 0.66 | EPHX1 (0.40) | L3MBTL1MEN1KMT2ALDLRRAB9A | |
| SCHEMBL1710420 | 0.65 | HAO1 (0.37) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27979216 | 0.64 | EPHX2 (0.38) | KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741742-A1 | METHODS FOR THE TREATMENT OF DIABETIC RETINOPATHY AND OTHER OPHTHALMIC DISEASES | Acucela Inc. (US) | 2020-11-25 | — | — | EP | disclosed |