SCHEMBL2270141

SCHEMBL2270141

CN[SiH](C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
HSD17B10 Q99714 4/20 0.36
ALDH1A1 P00352 5/20 0.35
TDP1 Q9NUW8 4/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
ALOX12 P18054 3/20 0.35
ALOX15 P16050 2/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
MAPK1 P28482 1/20 0.35
PTGS2 P35354 1/20 0.35
HTR2B P41595 1/20 0.35
KCNN4 O15554 1/20 0.35
MAPT P10636 4/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP3A4 P08684 2/20 0.33
TAAR1 Q96RJ0 3/20 0.32
ATM Q13315 2/20 0.32
RECQL P46063 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18143562 0.80 TSHR (0.35) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL2004808 0.76 TSHR (0.38) TSHRALOX12LMNAACHE
Dimethylamine SCHEMBL10623601 0.74 TSHR (0.41) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL2101602 0.74 TSHR (0.41) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL2268375 0.74 TSHR (0.41) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL8219011 0.74 TSHR (0.42) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL28215148 0.72 TSHR (0.46) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL23319721 0.72 TDP1 (0.41) TSHRHSD17B10ALDH1A1TDP1L3MBTL1
SCHEMBL8217607 0.72
SCHEMBL2272995 0.72 KCNN4 (0.36) TSHRHSD17B10ALOX12ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000665-B2 Hybrid material for optoelectronic applications AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2018-06-19 US disclosed
US-9991182-B2 Encapsulation material for light emitting diodes AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2018-06-05 US disclosed
US-20160362580-A1 HYBRID MATERIAL FOR OPTOELECTRONIC APPLICATIONS AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-12-15 US disclosed
US-20160172552-A1 ENCAPSULATION MATERIAL FOR LIGHT EMITTING DIODES AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-06-16 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed