Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702191 | 0.76 | ALDH1A1 (0.47) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL627479 | 0.75 | ADH1B (0.54) | ADH1BADH1CADH1AADH7IDO1 | |
| SCHEMBL19675583 | 0.74 | ADH1B (0.42) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL23188878 | 0.73 | ADH1B (0.41) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL17213800 | 0.73 | ADH1B (0.47) | ADH1BADH1CADH1AADH7IDO1 | |
| SCHEMBL7449229 | 0.73 | ADH1B (0.52) | ADH1BADH1CADH1AADH7IDO1 | |
| SCHEMBL20344487 | 0.73 | ADH1B (0.52) | ADH1BADH1CADH1AADH7IDO1 | |
| SCHEMBL23188929 | 0.73 | ADH1B (0.57) | ADH1BADH1CADH1AADH7SIGMAR1 | |
| SCHEMBL16903733 | 0.73 | ADH1B (0.47) | ADH1BADH1CADH1AADH7IDO1 | |
| SCHEMBL7449222 | 0.73 | ADH1B (0.52) | ADH1BADH1CADH1AADH7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096928-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-3319955-B1 | 6-AMINO-QUINOLINE-3-CARBONITRILS AS COT MODULATORS | GILEAD SCIENCES INC (US) | 2020-11-25 | — | — | EP | disclosed |